Opara is a multi-faceted designer whose work encompasses strategy, design and technology. His projects have included the design of brand identity, publications, packaging, environments, exhibitions, interactive installations, user interfaces and software, with many of his projects ranging across multiple media.

His clients have included Cooper Hewitt, Smithsonian Design Museum, Grace Farms, the Menil Foundation, the Studio Museum in Harlem, the Queens Museum, Santander, St. Regis Hotels, the Corcoran Group, Morgan Stanley, New York University, UCLA Architecture and Urban Design, Skidmore Owings & Merrill (SOM), Grimshaw Architects, (ARO) Architecture Research Office, Harry N. Abrams and Princeton Architectural Press.

Opara has won numerous awards including a Gold Cube from the Art Directors Club and honors from D&AD, the Society for Experiential Graphic Design (SEGD), Type Directors Club, Tokyo Type Directors Club, the American Institute of Graphic Arts (AIGA) and Communication Arts. His work is in the permanent collection of the Museum of Modern Art Opara is a senior critic at the Yale University School of Art.